What are aromatic amides?
Abstract. Aromatic amide foldamers constitute a growing class of oligomers that adopt remarkably stable folded conformations. The folded structures possess largely predictable shapes and open the way toward the design of synthetic mimics of proteins.
How are amides named?
Primary amides are named by changing the name of the acid by dropping the -oic acid or -ic acid endings and adding -amide. It is not necessary to include the location number in the name because it is assumed that the functional group will be on the end of the parent chain.
What is amide example?
An amide is an organic functional group with a carbonyl bonded to a nitrogen or any compound containing this functional group. Examples of amides include nylon, paracetamol, and dimethylformamide. The simplest amides are derivatives of ammonia. In general, amides are very weak bases.
What is NH group called?
In organic chemistry, amines (/əˈmiːn, ˈæmiːn/, UK also /ˈeɪmiːn/) are compounds and functional groups that contain a basic nitrogen atom with a lone pair. Inorganic derivatives of ammonia are also called amines, such as monochloramine (NClH2). The substituent -NH2 is called an amino group.
How are aromatic amides converted into aromatic amidines?
Aromatic amides (44) are converted into aromatic amidines via the imino chloride (normally by reaction with PCl 5 ). Two procedures have been widely used; the first involves heating the aryl amide, amine and phosphorus chloride in an inert solvent such as chloroform or benzene < 27JCS2318, 49JCS3043, 54JA920 >.
Which is an example of an aromatic amide foldamer?
Important examples of aromatic amide foldamers include oligomers of 7- or 8-amino-2-quinoline carboxylic acid that have been shown to exist predominantly as well-defined helices, including when they are combined with α-amino acids to which they may impose their folding behavior.
How are aromatic amides generated from acid halides?
Gilles Sauvé, Vanga S. Rao, in Comprehensive Organic Functional Group Transformations, 1995 Aromatic amides, generated from acids or acid halides, react with solutions of bromine or chlorine in sodium hydroxide to yield amines through a reaction known as the Hofmann rearrangement (Equation (38)) < 46OR (3)267, 49JA3929 >.
How are aryl amines related to aromatic amines?
Aryl amines are called aromatic amines and the simplest aromatic amine is the aniline. Aromatic amine: an amine in which nitrogen is bonded to one or more aryl groups. ): Nitrogen with three R groups • Quaternary amines (4° ): Ions in which nitrogen is bonded to four carbons and bears a positive charge.